HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 1-(4-Methoxyphenyl)-2-phenyl-4,5,6,7-tetrahydroindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | P-Anisidine | HCID 7732 | — |
| Reactant | 2-(2-Oxo-2-phenylethyl)cyclohexanone | HCID 10512899 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 1-(4-Methoxyphenyl)-2-phenyl-4,5,6,7-tetrahydroindole | HCID 13522538 | — |
Reaction Steps
Following a procedure similar to that of Example 1C but using 64.9 g. of 2-(2-oxocyclohexyl)acetophenone and 37 g. of 4-methoxyaniline in 180 ml. glacial acetic acid there was obtained 80.9 g. of 1-(4-methoxyphenol)-2-phenol-4,5,6,7-tetrahydroindole; m.p. 132°-133°C. (isopropyl alcohol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03968121 |
| Source dataset | uspto-grants-1976_07 |
| ORD ID | ord-e308877d423548a48c23363ebbd1ff24 |
| Source note | uspto-grants-1976_07 |