反应详情

25 ml of thionyl chloride are added dropwise to a solution of 20.4 g of methyl-(para-cyclohexylphenyl)-carbinol in 100 ml of benzene and 3 ml of pyridine, and the mixture then refluxed for 5 hours. It is then poured on to ice, the aqueous mixture is extracted with ether, and the ethereal solution washed with sodium bicarbonate solution and water. When the solution is dried and the ether evaporated, α-methyl-para-cyclohexyl-benzyl chloride is obtained in the form of a dark viscous liquid which is processed directly.

1. temperaturethe mixture then refluxed for 5 hours
2. additionIt is then poured on to ice
3. extractionthe aqueous mixture is extracted with ether
4. washthe ethereal solution washed with sodium bicarbonate solution and water
5. customWhen the solution is dried
6. customthe ether evaporated