Tert-Butylbenzene → 1-(4-Tert-butylphenyl)-2-methylbutan-1-one

HRID 917930Notes

Reaction equation

HRID 917930 reaction equation
[CH3:1][CH:2]([CH2:6][CH3:7])[C:3](Cl)=[O:4].[C:8]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)([CH3:11])([CH3:10])[CH3:9]>>[C:8]([C:12]1[CH:17]=[CH:16][C:15]([C:3](=[O:4])[CH:2]([CH3:1])[CH2:6][CH3:7])=[CH:14][CH:13]=1)([CH3:11])([CH3:10])[CH3:9]

Participants

3

Reactant 2

HCID 7366Tert-ButylbenzeneHCID 93697Butanoyl chloride, 2-methyl-

Product 1

HCID 134678071-(4-Tert-butylphenyl)-2-methylbutan-1-one

Procedure

The procedure of Example 3 was followed for the reaction of 60g (0.5 mole) of 2-methylbutyryl chloride with 67g (0.5 mole) of tert-butylbenzene. Obtained was 98.6g of a clear liquid: ir (film) 3.4 (s), 5.95 (s), 8.2 (m) microns; nmr (CDCl3) 7.66 (4H, d of d) 3.37 (1H, q), 1.77 (2H, m), 1.28 (9H, s), 1.16 (3H, d), 0.88 (3H, t) ppm. A VPC analysis indicated a single pure product.

Workup

  1. customObtained

Sources & evidence

ORD record
ord-8d3718df743840958d299aab15d66470
Source dataset
uspto-grants-1976_07
Patent number
US03968168

Reaction notes

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