Water → HCID 53827624, compound

HRID 918005Notes

Reaction equation

HRID 918005 reaction equation
[OH-].[Na+].[CH2:3]1[O:13][C:12]2[CH:11]=[CH:10][C:7]([CH2:8][OH:9])=[CH:6][C:5]=2[O:4]1.O.Cl[CH2:16][CH:17]=[C:18]([CH3:25])[CH2:19][CH2:20][O:21][CH:22]([CH3:24])[CH3:23]>C1C=CC=CC=1>[CH:22]([O:21][CH2:20][CH2:19][C:18]([CH3:25])=[CH:17][CH2:16][O:9][CH2:8][C:7]1[CH:10]=[CH:11][C:12]2[O:13][CH2:3][O:4][C:5]=2[CH:6]=1)([CH3:24])[CH3:23]

Participants

6

Reactant 4

HCID 962WaterHCID 10322Piperonyl alcoholHCID 14798Sodium HydroxideHCID 53822801HCID 53822801, compound

Product 1

HCID 53827624HCID 53827624, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

8.0 g (0.2 mol) of sodium hydroxide are added to a solution of 30.4 g (0.2 mol) of 3,4 -methylendioxy-benzylalcohol in 300 cc of benzene. The mixture is heated while stirring vigorously and kept at reflux temperature whereby the water condensing in a refrigerator is separated by means of a water separator. After 24 hours 35.3 g (0.2 mol) of 1-chloro-5-isopropoxy-3-methyl-2-pentene are added dropwise during the course of 1 hour and the mixture is stirred under reflux for a further 16 hours.

Workup

  1. temperatureThe mixture is heated
  2. temperatureat reflux temperature whereby
  3. customis separated by means of a water separator
  4. stirringthe mixture is stirred
  5. temperatureunder reflux for a further 16 hours

Sources & evidence

ORD record
ord-8332bbe2d8154e76846f9fb1f28f073e
Source dataset
uspto-grants-1976_07
Patent number
US03968235

Reaction notes

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