n-(3-Aminopropyl)benzamide → 1-[1(2-((5-Methyl-4-imidazolyl)methylthio)ethylamino)-2-nitrovinylamino]-3-[N'-cyano-N"-(2-(2-pyridylmethylthio)ethyl)guanidino]propane

Participants

Role	Name	HCID	Charge
Reactant	n-(3-Aminopropyl)benzamide	HCID 238993	—
Reactant	N-cyano-N'[2-(2-pyridylmethylthio)ethyl]-S-methylisothiourea	HCID 12889408	—
Reactant	1-nitro-2-methylthio-2-{2-[(4-methyl-1H-imidazol-5-yl)methylthio]ethylamino}ethylene	HCID 70456864	—
Product	1-[1(2-((5-Methyl-4-imidazolyl)methylthio)ethylamino)-2-nitrovinylamino]-3-[N'-cyano-N"-(2-(2-pyridylmethylthio)ethyl)guanidino]propane	HCID 178433675	—

Reaction Steps

1-Nitro-2-methylthio-2-[2-((5-methyl-4-imidazolyl)methylthio)ethylamino]ethylene was reacted with 3-benzoylaminopropylamine and the product was hydrolyzed under acidic conditions and reacted with N-cyano-N'-[2-(2-pyridylmethylthio)ethyl]-S-methylisothiourea to give the title compound.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US03968227
Source dataset	uspto-grants-1976_07
ORD ID	ord-361c63219c3243f8b25d50a29acead7c
Source note	uspto-grants-1976_07