Sulfuric Acid → HCID 22791426, compound

Participants

Reaction Steps

To 1 gm. of 9α-fluoro-11β-hydroxy-4-androstene-3,17 -dione in a solution of 1 ml. of triethylorthoformate in 7 ml. of dioxane add 0.6 ml. of 5% concentrated sulfuric acid in dioxane. Stir at room temperature for five minutes then add 1 ml. of pyridine and evaporate in vacuo to a residue. Add cold ethanol and filter off the resultant precipitate comprising 3-ethoxy-9α-fluoro-11β-hydroxy-3,5 -androstadiene- 3,17-dione (0.8 gm.).

Provenance & Evidence