4-(2-Aminoethyl)benzenesulfonamide → HCID 21522746, compound

HRID 918049Notes

Reaction equation

HRID 918049 reaction equation
CO[C:3]([C:5]1[N:9]=[C:8]([CH2:10][CH3:11])[O:7][N:6]=1)=[O:4].[NH2:12][CH2:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([S:21]([NH2:24])(=[O:23])=[O:22])=[CH:17][CH:16]=1>>[CH2:10]([C:8]1[O:7][N:6]=[C:5]([C:3]([NH:12][CH2:13][CH2:14][C:15]2[CH:16]=[CH:17][C:18]([S:21]([NH2:24])(=[O:22])=[O:23])=[CH:19][CH:20]=2)=[O:4])[N:9]=1)[CH3:11]

Participants

3

Reactant 2

HCID 1696824-(2-Aminoethyl)benzenesulfonamideHCID 54258213HCID 54258213, compound

Product 1

HCID 21522746HCID 21522746, compound

Procedure

Following the procedure of Example 1A, 5-ethyl-1,2,4-oxadiazol-3-carboxylic acid methyl ester is reacted wth p-(β-aminoethyl)-benzenesulfonamide to yield p-[β-(5-ethyl-1,2,4-oxadiazole-3-carbonylamino)ethyl]-benzenesulfonamide in almost quantitative yield, M.P. 159°-160°C. The compound can be recrystallized from methanol.

Sources & evidence

ORD record
ord-3212f07cd1fb45918192b3b54c92089d
Source dataset
uspto-grants-1976_07
Patent number
US03969365

Reaction notes

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