HCID 12279216, compound → HCID 131710390, compound

HRID 918061Notes

Reaction equation

HRID 918061 reaction equation
[Cl:1]C1C=CC2N(C)C(=O)C[N:8]3[C:14](C)=NN=[C:7]3[C:6]=2[CH:18]=1.[Cl:19][C:20]1[CH:21]=[CH:22][C:23]2[N:29]([CH3:30])[C:28](=[O:31])[CH2:27][N:26]3[C:32]([C:35](F)(F)F)=[N:33][N:34]=[C:25]3[C:24]=2[CH:39]=1>>[ClH:1].[Cl:19][C:20]1[CH:21]=[CH:22][C:23]([NH:29][CH3:30])=[C:24]([C:25]2[N:26]([CH2:27][C:28](=[O:31])[N:8]3[CH2:7][CH2:6][CH2:18][CH2:14]3)[C:32]([CH3:35])=[N:33][N:34]=2)[CH:39]=1

Participants

3

Reactant 2

HCID 12279216HCID 12279216, compoundHCID 12279219HCID 12279219, compound

Product 1

HCID 131710390HCID 131710390, compound

Procedure

Following the procedure of Example 1b but substituting an equivalent amount of 10-chloro-3,7-dimethyl-5H-s-triazolo-[4,3-d][1,4]benzodiazepin-6(7H)-one for the 10-chloro-7-methyl-3-(trifluoromethyl)-5H-s-triazolo[4,3-d][1,4]benzodiazepin-6(7H)-one, one obtains the titled compound.

Sources & evidence

ORD record
ord-3c2da937b6ae47318bb164ea82a3a0c3
Source dataset
uspto-grants-1976_07
Patent number
US03969366

Reaction notes

Loading…