5-Methyl-2-thiophenecarboxaldehyde → HCID 21436076, compound

HRID 918068Notes

Reaction equation

HRID 918068 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[C:6]([NH2:11])[CH:5]=1)([O-:3])=[O:2].C[C:13]1[S:17][C:16]([CH:18]=O)=[CH:15][CH:14]=1>C(O)C>[CH3:18][C:16]1[S:17][C:13](=[N:11][C:6]2[CH:5]=[C:4]([N+:1]([O-:3])=[O:2])[CH:9]=[CH:8][C:7]=2[OH:10])[CH2:14][CH:15]=1

Participants

4

Reactant 2

HCID 616635-Methyl-2-thiophenecarboxaldehydeHCID 36133892-Amino-4-Nitrophenol

Product 1

HCID 21436076HCID 21436076, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4Nitro-o-aminophenol (30.8 g, 0.2 mole) and 5-methyl-2-thiophenecarboxaldehyde (25.2 g, 0.2 mole) are dissolved in 250 ml of absolute ethanol and stirred at room temperature for 0.5 hour. The precipitated material is filtered and washed with additional ethanol yielding 49.8 g of product, melting point 202°-204°C.

Workup

  1. filtrationThe precipitated material is filtered
  2. washwashed with additional ethanol yielding 49.8 g of product, melting point 202°-204°C.

Sources & evidence

ORD record
ord-2bd68670870641859f39bb7179bc94e8
Source dataset
uspto-grants-1976_07
Patent number
US03969351

Reaction notes

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