HCID 21436074, compound → HCID 12781912, compound

Participants

Reaction Steps

2-[[(3-Methyl-2-thienyl)methylene]amino]-4-nitrophenol (13.1 g, 0.05 mole) is heated to reflux in 500 ml of glacial acetic acid and lead tetraacetate (22.2 g, 0.05 mole) is added to the hot mixture. After heating for 10 minutes, the mixture is diluted with 1 liter of water and the precipitated product collected. The crude material is dissolved in chloroform (350 ml) and treated with activiated charcoal. The chloroform is evaporated yielding 5.4 g of product, melting point 174°-176°C.

Provenance & Evidence