Water → HCID 21487894, compound

Participants

Reaction Steps

To a solution of 3 g of 2,4-furandione in 100 ml of benzene is added 4 g of tert-amylurea. The solution is heated under nitrogen at reflux for 3 hours with water removal. At the end of that period the solution is cooled and concentrated. The residual material is recrystallized from acetonitrile to give 2.5 g of 1-tert-amyl-3-(2,5-dihydro-5-oxo-3-furyl)urea, m.p. 169°-171°C. The infrared and n.m.r. spectra are consistent with the assigned structure.

Provenance & Evidence