Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Catechol | HCID 289 | — |
| Reactant | Phosphorus oxide (P4O10) | HCID 14812 | — |
| Reactant | Ethyl 3-(4-chlorophenyl)-3-oxopropanoate | HCID 101336 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 131710392 | HCID 131710392 | — |
Reaction Steps
98.9 g of P2O5 is added to a mixture of 64 g of ethyl p-chlorobenzoylacetate and 90.4 g of pyrocatechol, heated at 80°C in portions over about 1/2 hour. After 15 minutes the heating is interrupted and 1000 cc of benzene are added. The organic phase is decanted. The latter is repeatedly washed first with NaHCO3 and subsequently with H2O until same is rendered neutral and finally dried with Na2SO4. The solvent is removed in vacuum and the residual oil fractionated, b.p. 150°-155°C (0.4 mm.Hg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US03969368 |
|---|
| Source dataset | uspto-grants-1976_07 |
|---|
| ORD ID | ord-4855a72b436945e0ba8d988af23ca142 |
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| Source note | uspto-grants-1976_07 |
|---|
