Benzylamine → HCID 21412663, compound

HRID 918138Notes

Reaction equation

HRID 918138 reaction equation
[OH:1][C:2]1[CH:7]=[C:6]([CH:8]([CH3:12])[C:9]([OH:11])=[O:10])[CH:5]=[CH:4][C:3]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[CH2:19]([NH2:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>CCOCC>[OH:1][C:2]1[CH:7]=[C:6]([CH:8]([CH3:12])[C:9]([O-:11])=[O:10])[CH:5]=[CH:4][C:3]=1[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1.[CH2:19]([NH3+:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

4

Reactant 2

HCID 7504BenzylamineHCID 20333460HCID 20333460, compound

Product 1

HCID 21412663HCID 21412663, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

2-(2-hydroxy-4-biphenylyl)propionic acid (140 mg.) in ether (5 ml.) was mixed with benzylamine (62 g.) in ether (5 ml.). The precipitate was collected, washed with ether, dried in vacuo and recrystallised for absolute alcohol/ether to give benzylammonium 2-(2-hydroxy4-biphenylyl) propionate, m.p. 183° - 185°C.

Workup

  1. customThe precipitate was collected
  2. washwashed with ether
  3. customdried in vacuo
  4. customrecrystallised for absolute alcohol/ether

Sources & evidence

ORD record
ord-2f86c22c16f44c908af406e08772f3fc
Source dataset
uspto-grants-1976_07
Patent number
US03969402

Reaction notes

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