Water → HCID 54014341, compound

Participants

Reaction Steps

A solution of 6.0 gm (0.025 mol) of 4-(4'-biphenylyl- 3-butenoic acid (m.p. 188°C) in 100 ml of absolute tetrahydrofuran was dropwise stirred, at room temperature, into a suspension of 1.0 gm (0.026 mol) of lithium aluminum hydride in 100 ml of absolute ether. The mixture was stirred for a further 2 hours, then were successively added 1 ml of water, 2 ml of 2N sodium hydroxide solution and again 5 ml of water and the obtained precipitate was suction filtered. The solvent was distilled off from the filtrate, and the obtained firm residue was recrystallized from cyclohexane/ethyl acetate. The compound was obtained therefrom in a yield of 3.8 gm (68% of theory), m.p. 142°C, of the formula ##SPC9##

Provenance & Evidence