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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 918173Generated: October 31, 2026

4-Chloro-6-fluoro-2-methylquinoline → 6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline

https://huagongshe.com/reaction/918173

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-6-fluoro-2-methylquinolineHCID 87694—
CatalystRhodiumHCID 23948—
Product6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinolineHCID 591684—

Reaction Steps

4-Chloro-6-fluoroquinaldine was reduced with rhodium on carbon to give 6-fluoro-2-methyltetrahydroquinoline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03969463
Source datasetuspto-grants-1976_07
ORD IDord-a1d40acd1db942b9aa134665f5caa0ad
Source noteuspto-grants-1976_07