Ammonium → HCID 21523490, compound

Participants

Reaction Steps

The oil from Example 2 was dissolved in dried ether (25 ml.) and immediately added to phenylmagnesium bromide (prepared from 1.23g. magnesium and 8.00g. bromobenzene) in 150ml. dried ether. The mixture was stirred at room temperature for 16 hours. It was then poured on to a mixture of ammonium chloride (2.7g.) and ice and basified with ammonium solution. The solid remaining in the mixture was removed by filtration, and the ether layer was combined with chloroform extracts of the aqueous layer, dried over magnesium sulphate and evaporated to a residue. This residue and that from chloroform washings of the solid remaining after the Grignard reaction was crystallised from ethanol to give the title compound (0.56g.), m.p. 131°-3°C.

Provenance & Evidence