Methanol → HCID 21405007, compound

HRID 918204Notes

Reaction equation

HRID 918204 reaction equation
[CH2:1]([N:3]([CH2:24][CH3:25])[CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH:13]=[C:14]2[CH2:22][C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[C:15]2=O)=[CH:9][CH:8]=1)[CH3:2].CO.[CH3:28][NH:29][NH2:30]>>[CH2:1]([N:3]([CH2:24][CH3:25])[CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH:13]2[N:29]([CH3:28])[N:30]=[C:15]3[C:16]4[C:21]([CH2:22][CH:14]23)=[CH:20][CH:19]=[CH:18][CH:17]=4)=[CH:9][CH:8]=1)[CH3:2]

Participants

4

Reactant 3

HCID 887MethanolHCID 6061MethylhydrazineHCID 53713062HCID 53713062, compound

Product 1

HCID 21405007HCID 21405007, compound

Procedure

A solution of 26.4 g (0.08 mole) of 2-[[4-[2-(diethylamino)ethoxy]phenyl]methylene]-2,3-dihydro-1H-inden-1-one in 250 ml of methanol containing 3.7 g (0.08 mole) of methyl hydrazine is heated at reflux for 4 hours. After cooling, 9.1 g starting material is recovered.

Workup

  1. temperatureat reflux for 4 hours
  2. temperatureAfter cooling
  3. customis recovered

Sources & evidence

ORD record
ord-12cc54807a6e43b3923faf23d26f12dc
Source dataset
uspto-grants-1976_07
Patent number
US03969527

Reaction notes

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