HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrofluoric Acid → trans Ethyl 11-fluoro-3,7,11-trimethyldodeca-2,4-dienoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrofluoric Acid | HCID 14917 | — |
| Reactant | trans Ethyl 3,7,11-trimethyldodeca-2,4,10-trienoate | HCID 86733725 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | trans Ethyl 11-fluoro-3,7,11-trimethyldodeca-2,4-dienoate | HCID 86733724 | — |
Reaction Steps
One gram of trans ethyl 3,7,11-trimethyldodeca-2,4,10-trienoate is added to a solution of 1 equiv. of dry hydrogenfluoride in dry tetrahydrofuran. The mixture is allowed to stand at 0° for 15 hours and is then washed with water, dried and evaporated under reduced pressure to yield trans ethyl 11-fluoro-3,7,11-trimethyldodeca-2,4-dienoate which can be purified by chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03970704 |
| Source dataset | uspto-grants-1976_07 |
| ORD ID | ord-41a26b0ed936409280a4b03ab534de36 |
| Source note | uspto-grants-1976_07 |