Benzyl Chloride → 3-Benzyl-2,2,5,5-tetramethyl-4-oxo-imidazolidine

HRID 918359Notes

Reaction equation

[CH3:1][C:2]1([CH3:10])[NH:6][C:5](=[O:7])[C:4]([CH3:9])([CH3:8])[NH:3]1.[CH2:11](Cl)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH2:11]([N:6]1[C:5](=[O:7])[C:4]([CH3:9])([CH3:8])[NH:3][C:2]1([CH3:10])[CH3:1])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

Reactant 2

HCID 7503Benzyl Chloride

HCID 98127982,2,5,5-Tetramethyl-4-imidazolidinone

Product 1

HCID 215207973-Benzyl-2,2,5,5-tetramethyl-4-oxo-imidazolidine

Procedure

If, instead of 7,14-diaza-15-oxo-dispiro[5.1.5.2]pentadecane, 2,2,5,5-tetramethyl-4-oxo-imidazolidine is used, and this alkylated with benzyl chloride as described in Example 1, then 3-benzyl-2,2,5,5-tetramethyl-4-oxo-imidazolidine (VII), M.P. 210°C, is obtained.

Sources & evidence

ORD record: ord-0b39d41fc52a4d9daba8b65d702fd22b
Source dataset: uspto-grants-1976_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03971757

Reaction notes

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