HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Fluorouracil → HCID 15396958, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Fluorouracil | HCID 3385 | — |
| Reactant | 4-Nitrobenzoyl chloride | HCID 8502 | — |
| Product | HCID 15396958 | HCID 15396958 | 52.9% |
Reaction Steps
2.6 g (0.02 mole) of 5-fluorouracil was reacted with 9.28 g (0.05 mole) of p-nitrobenzoyl chloride in the same manner as in Example 1 and 2.95 g (52.9% yield) of 5-fluoro-1-(p-nitrobenzoyl)uracil was obtained. The product was recrystallized from ethanol and white needles melting at 182°-183°C. were obtained. The results of an elementary analysis of the above crystals were well in agreement with the calculated value as follows:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03971784 |
| Source dataset | uspto-grants-1976_07 |
| ORD ID | ord-9e17ca1782634605816a0fb2e707c29b |
| Source note | uspto-grants-1976_07 |