4-(7-Chloro-4-quinolylamino)benzoyl chloride hydrochloride → 4-(7-Chloro-4-quinolylamino)-N-(4-dimethylaminobutyl)-N-propyl-benzamide

HRID 918397Notes

Reaction equation

HRID 918397 reaction equation
Cl.[Cl:2][C:3]1[CH:12]=[C:11]2[C:6]([C:7]([NH:13][C:14]3[CH:22]=[CH:21][C:17]([C:18](Cl)=[O:19])=[CH:16][CH:15]=3)=[CH:8][CH:9]=[N:10]2)=[CH:5][CH:4]=1.[CH3:23][N:24]([CH3:33])[CH2:25][CH2:26][CH2:27][CH2:28][NH:29][CH2:30][CH2:31][CH3:32]>>[Cl:2][C:3]1[CH:12]=[C:11]2[C:6]([C:7]([NH:13][C:14]3[CH:22]=[CH:21][C:17]([C:18]([N:29]([CH2:28][CH2:27][CH2:26][CH2:25][N:24]([CH3:33])[CH3:23])[CH2:30][CH2:31][CH3:32])=[O:19])=[CH:16][CH:15]=3)=[CH:8][CH:9]=[N:10]2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 215209934-(7-Chloro-4-quinolylamino)benzoyl chloride hydrochlorideHCID 21520995N1,N1-dimethyl-N4-propyl-1,4-Butanediamine

Product 1

HCID 215209974-(7-Chloro-4-quinolylamino)-N-(4-dimethylaminobutyl)-N-propyl-benzamide

Procedure

4-(7-Chloro-4-quinolylamino)benzoyl chloride hydrochloride is reacted with 1 -dimethylamino-4-propylaminobutane in a similar manner to Example 1 to give the title compound.

Sources & evidence

ORD record
ord-a2d97b1575f84b6d94a903cd976a620d
Source dataset
uspto-grants-1976_07
Patent number
US03971787

Reaction notes

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