N,N-Dibutylethylenediamine → 4-Chloro-2-(7-chloro-4-quinolylamino)-N-(2-di-n-butylaminoethyl)benzamide

HRID 918431Notes

Reaction equation

HRID 918431 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=O)=[C:4]([NH:11][C:12]2[C:21]3[C:16](=[CH:17][C:18]([Cl:22])=[CH:19][CH:20]=3)[N:15]=[CH:14][CH:13]=2)[CH:3]=1.[CH2:23]([N:27]([CH2:31][CH2:32][CH2:33][CH3:34])[CH2:28][CH2:29][NH2:30])[CH2:24][CH2:25][CH3:26]>>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH:30][CH2:29][CH2:28][N:27]([CH2:23][CH2:24][CH2:25][CH3:26])[CH2:31][CH2:32][CH2:33][CH3:34])=[O:8])=[C:4]([NH:11][C:12]2[C:21]3[C:16](=[CH:17][C:18]([Cl:22])=[CH:19][CH:20]=3)[N:15]=[CH:14][CH:13]=2)[CH:3]=1

Participants

3

Reactant 2

HCID 77062N,N-DibutylethylenediamineHCID 215210034-Chloro-2-(7-chloro-4-quinolylamino)benzoic acid

Product 1

HCID 215210044-Chloro-2-(7-chloro-4-quinolylamino)-N-(2-di-n-butylaminoethyl)benzamide

Procedure

4-Chloro-2-(7-chloro-4-quinolylamino)benzoic acid is converted to the acid chloride which is reacted with 2-(di-n-butylamino)ethylamine as in Example 1 to give the title compound.

Sources & evidence

ORD record
ord-861caeb6def9434a8593b2c897e23969
Source dataset
uspto-grants-1976_07
Patent number
US03971789

Reaction notes

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