N,N-Dimethylpiperidin-4-amine → HCID 21521005, compound

HRID 918433Notes

Reaction equation

HRID 918433 reaction equation
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([NH:12][C:13]3[CH:21]=[CH:20][C:19]([I:22])=[CH:18][C:14]=3[C:15](O)=[O:16])=[CH:7][CH:8]=[N:9]2)=[CH:4][CH:3]=1.[CH3:23][N:24]([CH3:31])[CH:25]1[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1>>[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([NH:12][C:13]3[CH:21]=[CH:20][C:19]([I:22])=[CH:18][C:14]=3[C:15]([N:28]3[CH2:29][CH2:30][CH:25]([N:24]([CH3:31])[CH3:23])[CH2:26][CH2:27]3)=[O:16])=[CH:7][CH:8]=[N:9]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 417391N,N-Dimethylpiperidin-4-amineHCID 54231934HCID 54231934, compound

Product 1

HCID 21521005HCID 21521005, compound

Procedure

2-(7-Chloro-4-quinolylamino)-5-iodo benzoic acid is converted to the acid chloride which is reacted with 4-dimethylamino piperidine as in Example 1 to give the title compound.

Sources & evidence

ORD record
ord-f44d5f2ef53e498f8c0aa6865778dcba
Source dataset
uspto-grants-1976_07
Patent number
US03971789

Reaction notes

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