N,N-Dimethyl-1,3-propanediamine → HCID 21521009, compound

HRID 918435Notes

Reaction equation

HRID 918435 reaction equation
[F:1][C:2]([F:24])([F:23])[C:3]1[CH:12]=[C:11]2[C:6]([C:7]([NH:13][C:14]3[CH:22]=[CH:21][CH:20]=[CH:19][C:15]=3[C:16]([OH:18])=O)=[CH:8][CH:9]=[N:10]2)=[CH:5][CH:4]=1.[CH3:25][N:26]([CH3:31])[CH2:27][CH2:28][CH2:29][NH2:30]>>[CH3:25][N:26]([CH3:31])[CH2:27][CH2:28][CH2:29][NH:30][C:16](=[O:18])[C:15]1[CH:19]=[CH:20][CH:21]=[CH:22][C:14]=1[NH:13][C:7]1[C:6]2[C:11](=[CH:12][C:3]([C:2]([F:24])([F:1])[F:23])=[CH:4][CH:5]=2)[N:10]=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 7993N,N-Dimethyl-1,3-propanediamineHCID 1698112-((7-(Trifluoromethyl)-4-quinolinyl)amino)benzoic acid

Product 1

HCID 21521009HCID 21521009, compound

Procedure

2-(7-Trifluoromethyl-4-quinolylamino)benzoic acid is converted to the acid chloride which is reached with 3-dimethylaminopropylamine as in Example 1 to give the title compound.

Sources & evidence

ORD record
ord-c5f346b3ef024ceb9fa3285fa0083a39
Source dataset
uspto-grants-1976_07
Patent number
US03971789

Reaction notes

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