N,N-diethylpiperidin-4-amine → 1-[2-(7-Bromo-4-quinolylamino)-benzoyl]-4-diethylamino piperidine

HRID 918437Notes

Reaction equation

HRID 918437 reaction equation
[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([NH:12][C:13]3[CH:21]=[CH:20][CH:19]=[CH:18][C:14]=3[C:15]([OH:17])=O)=[CH:7][CH:8]=[N:9]2)=[CH:4][CH:3]=1.[CH2:22]([N:24]([CH2:31][CH3:32])[CH:25]1[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1)[CH3:23]>>[Br:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([NH:12][C:13]3[CH:21]=[CH:20][CH:19]=[CH:18][C:14]=3[C:15]([N:28]3[CH2:29][CH2:30][CH:25]([N:24]([CH2:31][CH3:32])[CH2:22][CH3:23])[CH2:26][CH2:27]3)=[O:17])=[CH:7][CH:8]=[N:9]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 2758239N,N-diethylpiperidin-4-amineHCID 215210062-(7-Bromo-4-quinolylamino)benzoic acid

Product 1

HCID 215210131-[2-(7-Bromo-4-quinolylamino)-benzoyl]-4-diethylamino piperidine

Procedure

2-(7-Bromo-4-quinolylamino)benzoic acid is converted to the acid chloride which is reacted with 4-diethylamino piperidine as in Example 1 to give the title compound.

Sources & evidence

ORD record
ord-1b0f58bfe98c4e8e947faee7d1e2e1f0
Source dataset
uspto-grants-1976_07
Patent number
US03971789

Reaction notes

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