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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 918500Generated: November 1, 2026

1,3-Cyclohexanedione → HCID 70635761, compound

https://huagongshe.com/reaction/918500

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-CyclohexanedioneHCID 10434—
Reactant2-CyanobenzaldehydeHCID 101209—
ReactantCarbamimidoyl-acetic acid ethyl esterHCID 4599837—
SolventEthanolHCID 702—
ProductHCID 70635761HCID 7063576149%

Reaction Steps

Upon heating a solution of 6.5 g of 2-cyanobenzaldehyde, 5.6 g of cyclohexane-1,3-dione and 6.5 g of amidinoacetic acid ethyl ester in 100 ml of ethanol for 5 hours, 2-amino-4-(2-cyanophenyl)-1,4,5,6,7,8-hexahydro-5-oxoquinoline-3-carboxylic acid ethyl ester of melting point 165°C (ethanol) is obtained. Yield: 49% of theory.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03971791
Source datasetuspto-grants-1976_07
ORD IDord-39ab7c67dd8b494b94acbfc011c54b9c
Source noteuspto-grants-1976_07