HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Isopropanol → Diethyl 2-amino-4-(2-furyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Isopropanol | HCID 3776 | — |
| Edukt | Ethyl 2-(furan-2-ylmethylidene)-3-oxobutanoate | HCID 252577 | — |
| Edukt | Carbamimidoyl-acetic acid ethyl ester | HCID 4599837 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | Diethyl 2-amino-4-(2-furyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate | HCID 4601376 | 78% |
Reaktionsschritte
Upon boiling a solution of 10.4 g of 2-furfurylideneacetoacetic acid ethyl ester and 6.5 g of amidinoacetic acid ethyl ester in 100 ml of ethanol for 2 hours, 2-amino-6-methyl-4-(fur-2-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester of melting point 183°C (isopropanol) is obtained. Yield: 78% of theory.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US03971790 |
| Quelldatensatz | uspto-grants-1976_07 |
| ORD ID | ord-e079a64ce05c47f7b59d93342696e3cc |
| Quellennotiz | uspto-grants-1976_07 |