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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 918521Generated: October 28, 2026

1,3-Cyclohexanedione → HCID 12391109, compound

https://huagongshe.com/reaction/918521

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-CyclohexanedioneHCID 10434—
Reactant2-NitrobenzaldehydeHCID 11101—
ReactantCarbamimidoyl-acetic acid ethyl esterHCID 4599837—
SolventEthanolHCID 702—
ProductHCID 12391109HCID 1239110969%

Reaction Steps

Upon heating a solution of 7.6 g of 2-nitrobenzaldehyde, 5.6 g of cyclohexane-1,3-dione and 6.5 g of amidinoacetic acid ethyl ester in 100 ml of ethanol for 2 hours, 2-amino-4-(2-nitrophenyl)-1,4,5,6,7,8-hexahydro-5-oxoquinoline-3-carboxylic acid ethyl ester of melting point 212°C (alcohol) is obtained. Yield: 69% of theory.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03971790
Source datasetuspto-grants-1976_07
ORD IDord-323c5cf37fe844669b2b6980f94ab419
Source noteuspto-grants-1976_07