反应详情

A stirred solution of 51.4 grams of (Z)-3,7-dimethyl-2,6-octadien-1-ol in 400 milliliters of dry ethyl ether, protected from light, is treated with 29.8 grams of phosphorous tribromide, dropwise, over a 1/2 hour period. The mixture is refluxed for about 2.5 hours, then cooled, poured on ice water and extracted with ether. The ethereal extract is washed with sodium bicarbonate, then with water and dried over sodium sulfate. Solvent is removed under reduced pressure to yield (Z)-1-bromo-3,7-dimethyl-2,6-octadiene.

1. temperatureThe mixture is refluxed for about 2.5 hours
2. temperaturecooled
3. additionpoured on ice water
4. extractionextracted with ether
5. extractionThe ethereal extract
6. washis washed with sodium bicarbonate
7. dry with materialwith water and dried over sodium sulfate
8. customSolvent is removed under reduced pressure