反应详情

28.3g (0.113 mol) of 2-bromo-p-chlorophenylacetic acid was mixed with 26.9g (0.226 mol) of thionylchloride and the mixture was refluxed for 2.5 hours. After the excess thionylchloride had been distilled off, the reaction mixture was distilled under reduced pressure to give 26.7g of 2-bromo-p-chlorophenylacetyl chloride as yellow-orange oil. (b.p. 148° - 152°C/15 mmHg)

1. temperaturethe mixture was refluxed for 2.5 hours
2. distillationAfter the excess thionylchloride had been distilled off
3. distillationthe reaction mixture was distilled under reduced pressure