HCID 21506073, compound → HCID 21506020, compound

HRID 918672Notes

Reaction equation

HRID 918672 reaction equation
C([O:3][C:4](=[O:26])[C:5]1[CH:10]=[C:9]([S:11](=[O:14])(=[O:13])[NH2:12])[C:8]([O:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[C:7]([NH:22][CH2:23][C:24]#[CH:25])[CH:6]=1)C.C(OC(=O)C1C=C(S(=O)(=O)N)C(OC2C=CC=CC=2)=C(NCC=C)C=1)C>>[O:15]([C:8]1[C:9]([S:11](=[O:14])(=[O:13])[NH2:12])=[CH:10][C:5]([C:4]([OH:26])=[O:3])=[CH:6][C:7]=1[NH:22][CH2:23][C:24]#[CH:25])[C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1

Participants

3

Reactant 2

HCID 21506073HCID 21506073, compoundHCID 21506135HCID 21506135, compound

Product 1

HCID 21506020HCID 21506020, compound

Procedure

By substituting ethyl-4-phenoxy-3-propargylamino-5-sulphamyl-benzoate for the ethyl-3-allylamino-4-phenoxy-5-sulphamyl-benzoate of Example 58 B and by recrystallizing from dilute ethanol, 4-phenoxy-3-propargylamino-5-sulphamyl-benzoic acid was obtained with a melting point of 222°-223°C.

Workup

  1. customby recrystallizing from dilute ethanol

Sources & evidence

ORD record
ord-bb748fd030b2438d98106b6234df2934
Source dataset
uspto-grants-1976_07
Patent number
US03971819

Reaction notes

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