HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 3-benzylamino-5-sulphamyl-4-(m-toluidino)-benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Benzoic acid,3-amino-5-(aminosulfonyl)-4-[(3-methylphenyl)amino]- | HCID 21506124 | — |
| Product | Ethyl 3-benzylamino-5-sulphamyl-4-(m-toluidino)-benzoate | HCID 21506091 | — |
Reaction Steps
A mixture of 3-amino-5-sulphamyl-4-(m-toluidino)-benzoic acid (1.5 g), benzyl bromide (2.5 g), and anhydrous ethanol (50 ml) was heated under reflux for 10 hours. The resulting solution was cooled, and the precipitated ethyl 3-benzylamino-5-sulphamyl-4-(m-toluidino)-benzoate was collected by suction. After recrystallization from ethanol, the compound had a melting point of 169-170°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03971819 |
| Source dataset | uspto-grants-1976_07 |
| ORD ID | ord-6fc8ca009fb34cd3b0c96a181fc5afb2 |
| Source note | uspto-grants-1976_07 |