3-Bromoquinoline → HCID 178519901, compound

Participants

Role	Name	HCID	Charge
Reactant	3-Bromoquinoline	HCID 21413	—
Reactant	1,3-Oxazol-4-ylmethanol	HCID 15930578	—
Reagent	Potassium Trimethylacetate	HCID 23662159	—
Catalyst	Bromo(thiobis(methane))copper	HCID 2724234	—
Catalyst	HCID 178486197	HCID 178486197	—
Solvent	1,4-Dioxane	HCID 31275	—
Product	HCID 178519901	HCID 178519901	—
Product	HCID 178519952	HCID 178519952	—
Product	HCID 178520002	HCID 178520002	—

Reaction Conditions

Temperature	100 °C

Reaction Steps

- reaction input `pd_catalyst` was added as a solution (2-methyltetrahydrofuran 1 mmol/L) and then the solvent was removed to leave solid solute before adding other reactants/reagents; - stirrer was added after `pd_catalyst` and before `base`; - reaction inputs were prepared inside a glove box but the reaction itself did not happen in a glove box; - the reaction vial was sealed after adding all reaction inputs

Provenance & Evidence

DOI	10.1039/d3dd00167a
Source dataset	C-H activation of oxazoles from the second demo case in the PyParser paper
ORD ID	ord-cedce95d2b904873b7472de60ff695ec
Source note	C-H activation of oxazoles from the second demo case in the PyParser paper