p-Aminoacetophenone → HCID 53364581, compound

Participants

Reaction Steps

Reaction of methyl 3-bromobenzoate with 4′-aminoacetophenone according to general procedure A provided methyl ester of 6 as a white solid (84% yield). 1H NMR (CDCl3, 500 MHz): δ=7.89 (d, J=8.7 Hz, 2H), 7.85 (s, 1H), 7.73 (m, 1H), 7.36-7.42 (m, 2H), 7.03 (d, J=8.5 Hz, 2H), 6.31 (s, 1H), 3.92 (s, 3H), 2.55 (s, 3H). 13C NMR (CDCl3, 125 MHz): δ=196.7, 167.0, 147.9, 141.3, 131.8, 130.9, 129.9, 129.8, 124.6, 124.2, 121.2, 115.1, 52.5, 26.4.

Provenance & Evidence