Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate → HCID 118113953, compound

HRID 918829Notes

Reaction equation

HRID 918829 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][NH2:9])=[CH:4][C:3]=1[O:10][C:11]([F:14])([F:13])[F:12].[Br:15][C:16]1[CH:17]=[CH:18][C:19]2[N:20]([CH:22]=[C:23]([C:25](OCC)=[O:26])[N:24]=2)[CH:21]=1>>[Br:15][C:16]1[CH:17]=[CH:18][C:19]2[N:20]([CH:22]=[C:23]([C:25]([NH:9][CH2:8][C:5]3[CH:6]=[CH:7][C:2]([F:1])=[C:3]([O:10][C:11]([F:13])([F:12])[F:14])[CH:4]=3)=[O:26])[N:24]=2)[CH:21]=1

Participants

3

Reactant 2

HCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylateHCID 177507021-[4-Fluoro-3-(trifluoromethoxy)phenyl]methanamine

Product 1

HCID 118113953HCID 118113953, compound

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate I, using (4-fluoro-3-(trifluoromethoxy)phenyl)methanamine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Sources & evidence

ORD record
ord-344d0e97031f4e1399c7370053718609
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

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