3-Fluoro-4-(trifluoromethyl)benzylamine → HCID 89741716, compound

HRID 918830Notes

Reaction equation

HRID 918830 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH2:12][NH2:13])[CH:5]=[CH:6][C:7]=1[C:8]([F:11])([F:10])[F:9].[Br:14][C:15]1[CH:16]=[CH:17][C:18]2[N:19]([CH:21]=[C:22]([C:24](OCC)=[O:25])[N:23]=2)[CH:20]=1>>[Br:14][C:15]1[CH:16]=[CH:17][C:18]2[N:19]([CH:21]=[C:22]([C:24]([NH:13][CH2:12][C:4]3[CH:5]=[CH:6][C:7]([C:8]([F:10])([F:11])[F:9])=[C:2]([F:1])[CH:3]=3)=[O:25])[N:23]=2)[CH:20]=1

Participants

3

Reactant 2

HCID 27375673-Fluoro-4-(trifluoromethyl)benzylamineHCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Product 1

HCID 89741716HCID 89741716, compound

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate I, using (3-fluoro-4-(trifluoromethyl)phenyl)methanamine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Sources & evidence

ORD record
ord-f96621dfabe548748627defbc3212a48
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

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