3-Chloro-4-fluoroaniline → HCID 118113934, compound

HRID 918832Notes

Reaction equation

HRID 918832 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[CH:7][C:8]=1[F:9])[NH2:5].[Br:10][C:11]1[CH:12]=[CH:13][C:14]2[N:15]([CH:17]=[C:18]([C:20](OCC)=[O:21])[N:19]=2)[CH:16]=1>>[Br:10][C:11]1[CH:12]=[CH:13][C:14]2[N:15]([CH:17]=[C:18]([C:20]([NH:5][C:4]3[CH:6]=[CH:7][C:8]([F:9])=[C:2]([Cl:1])[CH:3]=3)=[O:21])[N:19]=2)[CH:16]=1

Participants

3

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate I, using 3-chloro-4-fluoroaniline and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Sources & evidence

ORD record
ord-5838c70852464b39baccb44e275f3fea
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

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