Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate → 6-Bromo-N-(2-(4-fluorophenyl)propan-2-yl)imidazo[1,2-a]pyridine-2-carboxamide

HRID 918839Notes

Reaction equation

HRID 918839 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([NH2:11])([CH3:10])[CH3:9])=[CH:4][CH:3]=1.[Br:12][C:13]1[CH:14]=[CH:15][C:16]2[N:17]([CH:19]=[C:20]([C:22](OCC)=[O:23])[N:21]=2)[CH:18]=1>>[Br:12][C:13]1[CH:14]=[CH:15][C:16]2[N:17]([CH:19]=[C:20]([C:22]([NH:11][C:8]([C:5]3[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=3)([CH3:9])[CH3:10])=[O:23])[N:21]=2)[CH:18]=1

Participants

3

Reactant 2

HCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylateHCID 130256651-(4-Fluorophenyl)-1-methylethylamine

Product 1

HCID 1181139126-Bromo-N-(2-(4-fluorophenyl)propan-2-yl)imidazo[1,2-a]pyridine-2-carboxamide

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate I, using 2-(4-fluorophenyl)propan-2-amine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Sources & evidence

ORD record
ord-32258fe0aded4d7d8dd22a350a77f1fa
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

Loading…