Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate → HCID 118113942, compound

HRID 918840Notes

Reaction equation

HRID 918840 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([F:8])=[CH:4][C:3]=1[C:9]1([NH2:12])[CH2:11][CH2:10]1.[Br:13][C:14]1[CH:15]=[CH:16][C:17]2[N:18]([CH:20]=[C:21]([C:23](OCC)=[O:24])[N:22]=2)[CH:19]=1>>[Br:13][C:14]1[CH:15]=[CH:16][C:17]2[N:18]([CH:20]=[C:21]([C:23]([NH:12][C:9]3([C:3]4[CH:4]=[C:5]([F:8])[CH:6]=[CH:7][C:2]=4[F:1])[CH2:10][CH2:11]3)=[O:24])[N:22]=2)[CH:19]=1

Participants

3

Reactant 2

HCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylateHCID 45791187HCID 45791187, compound

Product 1

HCID 118113942HCID 118113942, compound

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate I, using 1-(2,5-difluorophenyl)cyclopropanamine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Sources & evidence

ORD record
ord-d9f195af6a514f248d984566e17625d3
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

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