1-[4-(4-fluorophenoxy)phenyl]methanamine → HCID 118113915, compound

HRID 918843Notes

Reaction equation

HRID 918843 reaction equation
[F:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][C:7]2[CH:12]=[CH:11][C:10]([CH2:13][NH2:14])=[CH:9][CH:8]=2)=[CH:4][CH:3]=1.[Br:17][C:18]1[CH:19]=[CH:20][C:21]2[N:22]([CH:24]=[C:25]([C:27](OCC)=[O:28])[N:26]=2)[CH:23]=1>>[Br:17][C:18]1[CH:19]=[CH:20][C:21]2[N:22]([CH:24]=[C:25]([C:27]([NH:14][CH2:13][C:10]3[CH:11]=[CH:12][C:7]([O:6][C:5]4[CH:15]=[CH:16][C:2]([F:1])=[CH:3][CH:4]=4)=[CH:8][CH:9]=3)=[O:28])[N:26]=2)[CH:23]=1

Participants

3

Reactant 2

HCID 38603771-[4-(4-fluorophenoxy)phenyl]methanamineHCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Product 1

HCID 118113915HCID 118113915, compound

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate I, using (4-(4-fluorophenoxy)phenyl)methanamine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Sources & evidence

ORD record
ord-dc48e0c038c449f69c3d8ad15acd07d0
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

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