Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate → HCID 118113981, compound

HRID 918848Notes

Reaction equation

HRID 918848 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([C:8]([F:11])([F:10])[F:9])[C:3]=1[CH2:12][NH2:13].[Br:14][C:15]1[CH:16]=[CH:17][C:18]2[N:19]([CH:21]=[C:22]([C:24](OCC)=[O:25])[N:23]=2)[CH:20]=1>>[Br:14][C:15]1[CH:16]=[CH:17][C:18]2[N:19]([CH:21]=[C:22]([C:24]([NH:13][CH2:12][C:3]3[C:4]([C:8]([F:10])([F:11])[F:9])=[CH:5][CH:6]=[CH:7][C:2]=3[Cl:1])=[O:25])[N:23]=2)[CH:20]=1

Participants

3

Reactant 2

HCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylateHCID 46737492HCID 46737492, compound

Product 1

HCID 118113981HCID 118113981, compound

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate I, using (2-chloro-6-(trifluoromethyl)phenyl)methanamine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Sources & evidence

ORD record
ord-3f9e389829eb4897a08f1ce74fdeda7c
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

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