4-Fluoro-2-(trifluoromethyl)aniline → HCID 118113895, compound

HRID 918851Notes

Reaction equation

HRID 918851 reaction equation
[F:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[C:4]([C:9]([F:12])([F:11])[F:10])[CH:3]=1.[Br:13][C:14]1[CH:15]=[CH:16][C:17]2[N:18]([CH:20]=[C:21]([C:23](OCC)=[O:24])[N:22]=2)[CH:19]=1>>[Br:13][C:14]1[CH:15]=[CH:16][C:17]2[N:18]([CH:20]=[C:21]([C:23]([NH:6][C:5]3[CH:7]=[CH:8][C:2]([F:1])=[CH:3][C:4]=3[C:9]([F:10])([F:11])[F:12])=[O:24])[N:22]=2)[CH:19]=1

Participants

3

Reactant 2

HCID 678534-Fluoro-2-(trifluoromethyl)anilineHCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Product 1

HCID 118113895HCID 118113895, compound

Procedure

The title compound was prepared by using procedures analogous to those described for the synthesis of Intermediate I, using 4-fluoro-2-(trifluoromethyl)aniline and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Sources & evidence

ORD record
ord-197f760becdd458b883b0dc8ca887040
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

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