2-(Trifluoromethyl)aniline → HCID 118113968, compound
Reaction equation
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:9]=[CH:8][CH:7]=[CH:6][C:4]=1[NH2:5].[Br:12][C:13]1[CH:14]=[CH:15][C:16]2[N:17]([CH:19]=[C:20]([C:22](OCC)=[O:23])[N:21]=2)[CH:18]=1>>[Br:12][C:13]1[CH:14]=[CH:15][C:16]2[N:17]([CH:19]=[C:20]([C:22]([NH:5][C:4]3[CH:6]=[CH:7][CH:8]=[CH:9][C:3]=3[C:2]([F:10])([F:11])[F:1])=[O:23])[N:21]=2)[CH:18]=1Participants
3
Procedure
The title compound was prepared by using procedures analogous to those described for the synthesis of Intermediate I, using 2-(trifluoromethyl)aniline and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.
Sources & evidence
- ORD record
- ord-4ae56cfbc12840d18da261d13ec02b6a
- Source dataset
- uspto-grants-2016_03
- Patent number
- US09271969B2
Reaction notes
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