2,5-Difluoroaniline → HCID 89740096, compound

HRID 918857Notes

Reaction equation

HRID 918857 reaction equation
[F:1][C:2]1[CH:8]=[CH:7][C:6]([F:9])=[CH:5][C:3]=1[NH2:4].[Br:10][C:11]1[CH:12]=[CH:13][C:14]2[N:15]([CH:17]=[C:18]([C:20](OCC)=[O:21])[N:19]=2)[CH:16]=1>>[Br:10][C:11]1[CH:12]=[CH:13][C:14]2[N:15]([CH:17]=[C:18]([C:20]([NH:4][C:3]3[CH:5]=[C:6]([F:9])[CH:7]=[CH:8][C:2]=3[F:1])=[O:21])[N:19]=2)[CH:16]=1

Participants

3

Reactant 2

HCID 677752,5-DifluoroanilineHCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Product 1

HCID 89740096HCID 89740096, compound

Procedure

The title compound was prepared by using procedures analogous to those described for the synthesis of Intermediate I, using 2,5-difluoroaniline and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Sources & evidence

ORD record
ord-8f0d9f7794c643b5b82b168a476bfe30
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

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