3,4,5-Trifluoroaniline → HCID 89741663, compound

HRID 918858Notes

Reaction equation

HRID 918858 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([F:10])[C:8]=1[F:9])[NH2:5].[Br:11][C:12]1[CH:13]=[CH:14][C:15]2[N:16]([CH:18]=[C:19]([C:21](OCC)=[O:22])[N:20]=2)[CH:17]=1>>[Br:11][C:12]1[CH:13]=[CH:14][C:15]2[N:16]([CH:18]=[C:19]([C:21]([NH:5][C:4]3[CH:3]=[C:2]([F:1])[C:8]([F:9])=[C:7]([F:10])[CH:6]=3)=[O:22])[N:20]=2)[CH:17]=1

Participants

3

Reactant 2

HCID 27249913,4,5-TrifluoroanilineHCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Product 1

HCID 89741663HCID 89741663, compound

Procedure

The title compound was prepared by using procedures analogous to those described for the synthesis of Intermediate I, using 3,4,5-trifluoroaniline and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Sources & evidence

ORD record
ord-be59be502bfd40468fb941771a8f65c8
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

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