2,4,6-Trimethylbenzylamine → 6-Bromo-N-(2,4,6-trimethylbenzyl)imidazo[1,2-a]pyridine-2-carboxamide

HRID 918862Notes

Reaction equation

HRID 918862 reaction equation
[C:1]1([CH3:11])[CH:6]=[C:5]([CH3:7])[CH:4]=[C:3]([CH3:8])[C:2]=1[CH2:9][NH2:10].[Br:12][C:13]1[CH:14]=[CH:15][C:16]2[N:17]([CH:19]=[C:20]([C:22](OCC)=[O:23])[N:21]=2)[CH:18]=1>>[Br:12][C:13]1[CH:14]=[CH:15][C:16]2[N:17]([CH:19]=[C:20]([C:22]([NH:10][CH2:9][C:2]3[C:1]([CH3:11])=[CH:6][C:5]([CH3:7])=[CH:4][C:3]=3[CH3:8])=[O:23])[N:21]=2)[CH:18]=1

Participants

3

Reactant 2

HCID 4584332,4,6-TrimethylbenzylamineHCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Product 1

HCID 1181139566-Bromo-N-(2,4,6-trimethylbenzyl)imidazo[1,2-a]pyridine-2-carboxamide

Procedure

The title compound was prepared by using procedures analogous to those described for the synthesis of Intermediate I, using mesitylmethanamine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Sources & evidence

ORD record
ord-ecf9e8fce41a4563830960b9e9bd89df
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

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