3-Chloroaniline → 2-Bromo-N-(3-chlorophenyl)imidazo[2,1-b]thiazole-6-carboxamide

HRID 918865Notes

Reaction equation

HRID 918865 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[CH:7][CH:8]=1)[NH2:5].[Br:9][C:10]1[S:14][C:13]2=[N:15][C:16]([C:18](O)=[O:19])=[CH:17][N:12]2[CH:11]=1>>[Br:9][C:10]1[S:14][C:13]2=[N:15][C:16]([C:18]([NH:5][C:4]3[CH:6]=[CH:7][CH:8]=[C:2]([Cl:1])[CH:3]=3)=[O:19])=[CH:17][N:12]2[CH:11]=1

Participants

3

Reactant 2

HCID 79323-ChloroanilineHCID 127446152-Bromoimidazo[2,1-b]thiazole-6-carboxylic acid

Product 1

HCID 1181139062-Bromo-N-(3-chlorophenyl)imidazo[2,1-b]thiazole-6-carboxamide

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate XLVI, using 3-chloroaniline and 2-bromoimidazo[2,1-b]thiazole-6-carboxylic acid as starting materials.

Sources & evidence

ORD record
ord-b0190922e4a5468a9664e431d46c1094
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

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