3-(Trifluoromethoxy)benzylamine → 2-Bromo-N-(3-(trifluoromethoxy)benzyl)imidazo[2,1-b]thiazole-6-carboxamide

HRID 918868Notes

Reaction equation

HRID 918868 reaction equation
[F:1][C:2]([F:13])([F:12])[O:3][C:4]1[CH:5]=[C:6]([CH2:10][NH2:11])[CH:7]=[CH:8][CH:9]=1.[Br:14][C:15]1[S:19][C:18]2=[N:20][C:21]([C:23](O)=[O:24])=[CH:22][N:17]2[CH:16]=1>>[Br:14][C:15]1[S:19][C:18]2=[N:20][C:21]([C:23]([NH:11][CH2:10][C:6]3[CH:7]=[CH:8][CH:9]=[C:4]([O:3][C:2]([F:12])([F:13])[F:1])[CH:5]=3)=[O:24])=[CH:22][N:17]2[CH:16]=1

Participants

3

Reactant 2

HCID 1452643-(Trifluoromethoxy)benzylamineHCID 127446152-Bromoimidazo[2,1-b]thiazole-6-carboxylic acid

Product 1

HCID 1181138922-Bromo-N-(3-(trifluoromethoxy)benzyl)imidazo[2,1-b]thiazole-6-carboxamide

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate XLIV, using (3-(trifluoromethoxy)phenyl)methanamine and 2-bromoimidazo[2,1-b]thiazole-6-carboxylic acid as starting materials.

Sources & evidence

ORD record
ord-c62abc02bc674c8dadc7cd3ff160c94d
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

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