4-Isopropylbenzylamine → 2-Bromo-N-(4-isopropylbenzyl)imidazo[2,1-b]thiazole-6-carboxamide

HRID 918871Notes

Reaction equation

HRID 918871 reaction equation
[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][NH2:11])=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[Br:12][C:13]1[S:17][C:16]2=[N:18][C:19]([C:21](O)=[O:22])=[CH:20][N:15]2[CH:14]=1>>[Br:12][C:13]1[S:17][C:16]2=[N:18][C:19]([C:21]([NH:11][CH2:10][C:7]3[CH:8]=[CH:9][C:4]([CH:1]([CH3:3])[CH3:2])=[CH:5][CH:6]=3)=[O:22])=[CH:20][N:15]2[CH:14]=1

Participants

3

Reactant 2

HCID 1382214-IsopropylbenzylamineHCID 127446152-Bromoimidazo[2,1-b]thiazole-6-carboxylic acid

Product 1

HCID 1181138902-Bromo-N-(4-isopropylbenzyl)imidazo[2,1-b]thiazole-6-carboxamide

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate XLIV, using (4-isopropylphenyl)methanamine and 2-bromoimidazo[2,1-b]thiazole-6-carboxylic acid as starting materials.

Sources & evidence

ORD record
ord-4546090859ec42a9bfb5e90896f4217a
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

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