2-Bromoimidazo[2,1-b]thiazole-6-carboxylic acid → HCID 118113937, compound

HRID 918873Notes

Reaction equation

HRID 918873 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([O:9][C:10]([F:13])([F:12])[F:11])=[CH:5][C:4]=1[CH2:14][NH2:15].[Br:16][C:17]1[S:21][C:20]2=[N:22][C:23]([C:25](O)=[O:26])=[CH:24][N:19]2[CH:18]=1>>[Br:16][C:17]1[S:21][C:20]2=[N:22][C:23]([C:25]([NH:15][CH2:14][C:4]3[CH:5]=[C:6]([O:9][C:10]([F:12])([F:11])[F:13])[CH:7]=[CH:8][C:3]=3[O:2][CH3:1])=[O:26])=[CH:24][N:19]2[CH:18]=1

Participants

3

Reactant 2

HCID 127446152-Bromoimidazo[2,1-b]thiazole-6-carboxylic acidHCID 231921181-[2-Methoxy-5-(trifluoromethoxy)phenyl]methanamine

Product 1

HCID 118113937HCID 118113937, compound

Procedure

The title compound was prepared by essentially following the same procedures described for Intermediate XLIV, using (2-methoxy-5-(trifluoromethoxy)phenyl)-methanamine and 2-bromoimidazo[2,1-b]thiazole-6-carboxylic acid as starting materials.

Sources & evidence

ORD record
ord-f74724b531f94cdd8aaa65bf46a14dbb
Source dataset
uspto-grants-2016_03
Patent number
US09271969B2

Reaction notes

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